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1.
Not pleasant to look at.
Man, those hating witches are so aesthetically challenged. Their faces are eye-gouging inducive. It really makes me sick to look in their general direction.
by GoJesus! April 02, 2009
20 5
 
2.
Someone who is considered to be unattractive.
Dang, he's seriously aesthetically challenged, somebody make it stop.
by Honsho November 27, 2009
11 0
 
3.
A euphemism for ugly. A politically correct term similar to "mentally challenged", "vertically challenged", and "horizontally challenged". (Which mean retarded, short, and fat, respectively.
"In Washington D.C. and Santa Cruz, California, it's actually illegal to discriminate against people who are aesthetically challenged. Damn liberals..."

"I'm not ugly! I'm just *aesthetically challenged*!"
by Harlequin Princess September 30, 2009
12 2
 
4.
Unable to appreciate art, beauty and sensualism.
There is no point in taking mom to the museum, she's aesthetically challenged.
by NearlyMad February 25, 2014
1 0