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Instead of newer genres, it's more an older, rough, tough 'biker' usage... for someone to be wary of, aware of, watch out for, cognizant of... used informatively, often as a warning.
sarcasticly - similar to 'a real nice guy', 'a real sweetheart'
"You'd better watch out for that one, he's a real mother... "
by realisms June 04, 2010