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The popular yaoi, or 'boys love' pairing of the characters Roronoa Zoro and Sanji from the manga and anime series One Piece. It originates from their names, 'Zoro' contributing to the 'Zo' and 'Sanji' contributing to the 'San'. It is usually referenced for Zoro being the seme, or 'top', and if Sanji 'tops' it is known as 'SanZo'.
One Piece fan - "My OTP is totally ZoSan!"

One Piece fan 2 - "Nah, I personally prefer ZoLu!"
by LiteratureLove September 29, 2012