The saying "Nuke the Zanes!" is a reference to the Zanies, usually used by people who don't approve of the Zany lifestyle.
Person two: Who would have thought a person would do a tripple backflip and land on a cactus
I sometimes let zany slip from time to time, i say it in a surfer dude voice like "Wow! What a zany guy" but mostly I use it sarcastically, by that I mean I say that Richard Nixon is zany. Nixon actually was a thieving, Cheneyesque, monster. Maybe some day zany will make a big comeback, most likely from the streets of Jamaica Queens.