If you poop yourself in your bed, while you are sleeping.
"I woke up and found out that i made a yozo in my bed."
by Spinbar April 1, 2021
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Same As A Yo-Yo but used With A Faggot called Yozo instead.
by Anonymous May 22, 2003
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You only zing once. From the movie Hotel Transylvania, used between the vampire Mavis and the human Jonathan. Used to mean that you only fall in love with that one person who just perfect for you once.
Girlfriend: "I'm so glad we're in love. We're so lucky. We're perfect for each other!"

Boyfriend: "I know, right? After all, YOZO!"
by TheProphecy February 9, 2013
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You Only Zombie Once. Same as YOLO except once you get bit a zombie there's no going back so might as well live it up before you turn into a flesh eating crazy person!
"Yo do you want to go out and get crazy drunk and dance till you fall over?"

"YOZO!!!!"

"Dude i think that crazy girl is into you. Dare you to ask her out."

"YOZO!!!"
by Madrabid November 2, 2012
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one awsome dude, chillen at his house is the best with all the boys and he makes rad food and plays some sweet guitar wilst we dang it on the couch/computer
man jam-yozo is one awsome dude cant wait to dang it at hes againg
by Zaphex October 30, 2007
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