The phrase used to break up with that person (usually a boyfriend or a girlfriend) who is toxic to you. It keeps it simple, the best way.
"What do you mean you're not coming over on Saturday night? What else do you have to do? We always watch basketball or hockey or football or (worse yet) golf, and you bring the pizza and beer, and we hang."
"Not this Saturday night or any other night after that, Fred, you deplete me. Mind, wallet, and soul. Buh-bye."