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1.
This is a short form of 'Yes ma'am'. When used to a guy, it is a slight and unnoticed insult. Very good for an annoying boss.
Your mother: "Get your ass working now!"
You: "Yes'm."

Your boss: "Get your ass working now!"
You: ( snickering ) "Yes'm."
by Mikhail Bodeau June 29, 2004
 
2.
A shortened version of yes ma'am, much like yessum, though it's even shorter than that. Used by them lazy folk who dang can nay type no good.
<person 1> I want you to fry the vegetables, clean the pantry, and shave your god damn balls.
<person 2> Yes'm.
by Alanax0rz May 23, 2004
 
3.
one syllable, similar to "ism"

basically "yes", originally a shortening of "yes ma'am" but gradually becoming used in almost all contexts in which yes is used.
"Hey you there?"
"Yesm"
by Mallio June 09, 2003
 
4.
Yesm brought about by shortening Yes ma'am or yes Man.
Also a typographical error.
The M Is next to the comma.

Yesm I totally agree with you!
*Yes, I totally agree with you!
by anigrl May 30, 2007
 
5.
A quick and easier way of saying "yes man".
guy 1: you still there?
guy 2: yesm
by peek-a-boo August 04, 2004
 
6.
another way of saying yes
first used by anthony and not by others.
"So did you have a good time today?"
"yesm"
by ayato November 21, 2007