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1.
Acronym in the internet startup community for "you only hit one million once", referring to obtaining your first million users.

Originates from yolo, but instead of the battle cry for moronic decisions, events prefixed or suffixed with YOHOMO tend to be related to first world problems.
Jason: Our 1M user party is going to be a disaster: we're out of fridge space for the Svedka.

Matt: Bro, just expense a new fridge. #YOHOMO.
by Phronesis June 07, 2012
3 0
 
2.
a super gay girl who can't admit that she's gay even though everybody knows it and calls her out on it
"yo, check out that girl right there! so gay!"
"YOHOMO!!!!!"
by justsayin69696 March 27, 2012
0 0