A combination of Xilinx (software) and faulure, XilinxFail. Failure of industrial, professional software applications, where one would expect it to work flawless.
Origin: Xilinx WebPack software is unintuitive and full of bugs. University students found their projects far from succesful while using this software.
Sue: My *APPNAME* has crashed again!
Peter: Oh NO! XilinxFail!