2 more definitions
A greeting used amongst people in urban setting. It can be used in several ways. It can express freindship,anger or a question. Used extensively in the upper east of the midwest; mainly Detroit.
(to a group of people) What up do!? (retrun answer) What up do!!
by Aristidis Alexopoulos April 02, 2007
Greeting meaning hello, or most likely hi, it is said in a deep tone, and with feeling.
What up do nigga!
by Terry Fields May 19, 2003