look up any word, like eiffel tower:
 
1.
A greeting such as Hello my friend, How are you doing today.
"What they do cuz?"

"Chillin at my krib"
by Tommy November 22, 2003
 
2.
Origin - Southeast. A replacement for "What's up?"
"What they do, lil' mama?"
by KK From Around the Way May 14, 2005
 
3.
A greeting to find out how someone is feeling and what plans they have or will have.
Hey yo Mike, whattheydo? What's up for later?
by Whitney Bryant February 19, 2007