In reference to any diseased-ridden vaginus; by definition, any female genitalia harboring a minimum of 4 STD's; in certain contexts can be used in reference to a female mosquito.
Boner: "Son, it is very important that you always wear a condom when you are fornicating with one of your concubines."
Son: "Don't worry Dad. I'm just intercoursing with the harlot who lives down the street. She's on birth control!"
Boner: "Oh no son. You should at least triple wrap before planting your tree in that West Nile snatch."