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1.
1) The act of targeting and destroying a deliberately sarcastic joke's humor by stating the obvious facts which are being mocked.

2) Demonstrating a gross disregard that a joke has been made.
Person 1: "Actually, these are O.R. scrubs."
Person 2: "Oh... Are they?"
(Persons 1 and 2 share a rich laugh)
Person 3: "Well, in this case, the letters 'O' and 'R' stand for 'operating room.'"
Person 2: "Well, shit... you are a master of weseling jokes, bro."
by Matador Crabs March 20, 2013