Stands for What Is Fucking Wrong. Used when someone nags a lot and you just want to tell them to get to the point. Also used when something weird happens and you don't know what is going on.
Example 1:

Guy 1: Dude, I am soo mad.

Guy 2: You have been mad this entire week. Now STFU if you won't tell me WIFW.

Example 2:

*The day after the BP oil leak*

Guy: WIFW with BP!!!
by parklane79 July 26, 2010

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