Top Definition
A syndrome that affects some men, rendering them inable to do anything without the best guy friends with them at all times. This includes, growing up, living in a house, and dating. Inflicted guy is surrounded by his bros at all times and they make all of his life decisions together, in essence if you are dating a guy with VCS you are basically dating his friends too.
A good example of Vince Chase Syndrome is its name sake. Vinnie Chase from the appropriately titled series Entourage. In where Vinnie goes no where and does nothing without his entourage of male companions.
by pstang December 11, 2010
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