Top definition
When you drink for several days straight with minimal sleep and food. It culminates with the person passing out and waking up with a four day hangover.
You: ....Huh... Where am I?

Paramedic: "Sir, you've passed out. Did you just get back from Vegas? I've seen this before. It's Vegas syndrome."
by Mikey Miller from El Cajon November 02, 2008
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