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1.
a fictional equation created by the tv show LOST.
The "Lost Experience" has revealed that the objective of the DHARMA Initiative is to alter any of the six factors of the Valenzetti Equation, revealed to have a huge impact on the date the human race will destroy itself, whether by global warming, chemical warfare, overpopulation or many other possible methods. These factors are represented as numbers in the Valenzetti Equation and are also the numbers frequently mentioned in the show: 4, 8, 15, 16, 23 and 42.

The DHARMA initiative works with the Valenzetti Equation
by Khayman November 06, 2006