Top Definition
A VD Slut is a chick that is a major whore, and has like a million different venereal diseases.
"I hate that fucking VD Slut. She's so fuckin' slutty I got herpes just looking at her."

"That bitch is such I VD Slut, their no way I would screw her."
by Mike Oxbig February 23, 2005

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