To be Upside down is to have an alcohol hang over, that also includes weed hangover. This happens when the night before you have been drinking and smoking Marijuana a lot. The feeling includes headache, stomachache, bad taste, dry through, weird thoughts, accessional sleepiness, and with that weird dreams.
"Im an jsut so upsidedown today, i barley got anysleep last ngiht formt he party"
by Dieweak73 May 12, 2008