The disorder in which a person's Down syndrome is so severe that his face is completely rotated out of proportion. More severe cases can affect muscle girth, especially in the forearms. This renders the victim's forearms indistingiushable from pencils. One's speech may also become unamusing and trite.
Chris Max, what's up with your face?
Max BABABABAABaabaaba!!!
Chris O, you must have Upside Down syndrome, which renders yours forearms indistingiushable from pencils. My bad.
by max_fisk November 27, 2008
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Term used to describe someone who is excessively ugly. If the ugliness is beyond compare use Backflip Upside Down Syndrome
John - "Yo, check out that guy over there!"

Jane - "Man, he looks like he has upside down syndrome."

Jen - "Yeah! That girl looks like she has backflip upside down syndrome!"

John - "Harsh."
by dczech August 26, 2008
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The disorder in which a person's Down syndrome is so severe that his face is completely rotated out of proportion. More severe cases can affect muscle girth, especially in the forearms. This renders the victim's forearms indistingiushable from pencils. One's speech may also become unamusing and trite.
Chris Max, what's up with your face?
Max BABABABAABaabaaba!!!
Chris O, you must have Upside Down Syndrome, which renders yours forearms indistingiushable from pencils and your speech unwitty. My bad.
by R. Areaux February 16, 2009
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The disorder in which a person's Down syndrome is so severe that his face is completely rotated out of proportion. More severe cases can affect muscle girth, especially in the forearms. This renders the victim's forearms indistingiushable from pencils. One's speech may also become unamusing and trite.
Chris Max, what's up with your face?
Max BABABABAABaabaaba!!!
Chris O, you must have Upside Down Syndrome, which renders yours forearms indistingiushable from pencils and your speech unwitty. My bad.
by R. Areaux February 16, 2009
Get the Upside Down Syndrome mug.
The disorder in which a person's Down syndrome is so severe that his face is completely rotated out of proportion. More severe cases can affect muscle girth, especially in the forearms. This renders the victim's forearms indistingiushable from pencils. One's speech may also become unamusing and trite.
Chris Max, what's up with your face?
Max BABABABAABaabaaba!!!
Chris O, you must have Upside Down Syndrome, which renders yours forearms indistingiushable from pencils and your speech unwitty. My bad.
by R. Areaux February 16, 2009
Get the Upside Down Syndrome mug.
The disorder in which a person's Down syndrome is so severe that his face is completely rotated out of proportion. More severe cases can affect muscle girth, especially in the forearms. This renders the victim's forearms indistingiushable from pencils. One's speech may also become unamusing and trite.
Chris Max, what's up with your face?
Max BABABABAABaabaaba!!!
Chris O, you must have Upside Down Syndrome, which renders yours forearms indistingiushable from pencils and your speech unwitty. My bad.
by R. Areaux February 16, 2009
Get the Upside Down Syndrome mug.