Top Definition
a slogan (using rhymns) that's been used in the past by the Rev. Jesse Jackson.
Up with Hope, Down with Dope sounds like a positive notion, but when the children grow up and have to face the problems and stresses of life where dumbasses are in unearned positions of power and they try to influence every aspect of our lives then some may lose hope. Then how do they try to cope and meet demands? You guessed it - DOPE!
by I Saw U2 Live Twice January 14, 2009

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