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1.
The unfortunate process that certain hot people from high school go through that renders them borderline hideous.
Man, did you see Henry? Time was not good to him since high school...he obviously went through some severe uglifi'cation.
by MLeeAnn October 22, 2011
 
2.
To make an otherwise valuable object less aesthetically appealing in an attempt to keep it from getting stolen. Related to ghettofied if the uglification process involves bling. If the uglification is expertly accomplished, the result may be uglicious.
Because bike thefts are a major problem in China, Bobby put his bike through an uglification process--wrapping it in masking tape, spray painting it, and throwing dirt on it--in order to make it less appealing to thieves.
by vanilla_coke October 31, 2007