The utter most ghetto area of a state or providence, mainly populated by "hardcore" and "druggie" stereotypes.
There is no way in hell i'm going down to U-town after dark!
by stephanie isB0SS June 15, 2008
better known as University City, county of St. Louis, MO, birthplace of the St. Lunatics, and home to the dopest drumline anywhere.
Up in U Town, man, they know how to get down...
by Zaggs October 14, 2005
Urbana, Illinois. U town Killas is the hip-hop group that began using this term to talk about their hood, and it quickly spread around Urbana- Champaign, Illinois though it has not caught on to a larger speaking audience probably because Urbana-Champaign remains unknown to most people.
We some U town killas
by dudero July 27, 2006