Top Definition
a way of saying "peace", often used as a sign off or a symbol of one's departure. the name is derived from the two fingers that go up when making a peace sign with a hand.
Rick: "Remember that we gotta' pick up Susan tomorrow."
Bill: "Alright, man, i'll remember. I'm calling it a night. Two up."
by Kid Glorious March 20, 2010

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(drunkspeak) To one-up someone's one-up, or to severely one-up someone.
Soberguy- Always trying to one-up me, aren't you...
Drunkguy- I'll two-up you....
by atomicdonkey February 14, 2005

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Simoultaneous sex with a womans rear and front entry
Ooooh that must hurt!
by Rear entry Reg November 19, 2003

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