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1.
Term used to describe someone incapable of drinking alcohol, such that if they drink any more than two pints of lager they start to behave like a twat.

Also used to describe a wimp who insists that alcohol is the root of all evil and only concedes to it "for medicinal purposes".
"Nah, I'm not going if Dave is, he's a two pint screamer, he'll show us up"

"... and a coke with ice for Darren, cos he's a two pint screamer"
by Mr.T, I pity da fool! October 14, 2004