look up any word, like half chub:
 
1.
a person who stays up 14 days in a row. usualy on drugs... but it can be done sober.
bill is such a tweeker that hes become a twoweeker.
by jacks of appleness July 09, 2012
 
2.
People who sag there pants in such a way that it appears that they have two weeks worth of shit in them.
Person 1: Hey there your sporting the Two Weeker look

Person 2: The fuck you talkin bout old man

Person 3: Your pants are sagging In such a way that it appears you have two weeks worth of shit in them.
by II Duce May 30, 2010
 
3.
A girl or guy that you suddenly fall in love with for about two weeks until you realize what an ugly fucking bitch they are
I wasn't in love with her, she was only a two-weeker.
by d.j. unC.O.N.shuss November 01, 2009