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3.
A latino street gang named after 26th ST in Chicago's Little Village community. The gang was originally a neighboorhood baseball team called the Two Sixers but formed as a street gang in the 1960's. One of Two six's biggest rivals is the Latin Kings.
Hey ese, look at that vato walkin down 26th, he wearin' black & tan, he must be a Two Six.
by Little Village Vendor July 12, 2009
53 63
 
1.
a 26 ounce or 750mL bottle of alcohol
i got a two six of vodka, its time to party
by mr happy January 05, 2004
448 49
 
2.
A Canadian term for a 26-ounce bottle of alcohol. The modern bottle is actually 750 mL (25.36 oz), but it is still commonly called a two-six nonetheless. (See also: two-four.)
I finished off a two-six of rum in one evening, and did not feel good the next morning.
by Some Guy (2q38f7bdo73h2sdlh) October 12, 2005
164 22
 
4.
The act of being extremely cheap.
That cheap-ass didn't tip again! He's always two-sixing me!
by White Kiwi July 10, 2008
14 58
 
5.
A slang term for b.o. otherwise known as body odour. The numbers stand for the letters, they way they appear on a telephone keypad.
"The guy next to me ordering a drink had the worst two six."
by KJ March 01, 2005
18 346