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1.
A grip is: n. a phrase used to express quantity; a large amount of something.

Two grips would be way more than one grip: an extremely large amount (approx. equivalent to a metric fuckton) often used as an exaggeration for alot of stuff
"Man this mac n cheese is so cheesy! You got all kinds a cheese up in this bitch!"

"Its because I put two grips of cheese in it!"

"Two grips of weed is a shitload more than one grip!"
by synaesthetic May 19, 2010