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1.
When an obese man has rather large man boobs that get so sweaty they twinkle in the sun light.

"Oh man, Brian should wipe his twinkle tits, he's blinding me!"
by Gunther Gumball February 22, 2008
 
2.
Both nipples pierced, glinting magnificently by dawn's early light.
Evan Davies is known as "twinkle tits" by the presenters of Radio 4's Today Programme, because of his pendulously glittery nips.
by Dragon's Den September 14, 2010