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1.
A person who tweets way to much, usually about boring or every day activities that noone cares about
joe: yo did you follow that hot girl on twitter yet?
joe#2:yea dude, she tweets so much, like every 36 seconds. its so annoying.
joe: wow sounds like shes a tweet twat
by Johnnybertone November 30, 2011
 
2.
A female who twitters hateful, or drama causing statements on the Twitter network.
Sheila is such a tweet-twat she is always talking shit on my page.
by Twila Magoo July 16, 2010