Top Definition
slang term for an area of a city or town, or even an entire city or town with an extraordinarily high number of tweakers, aka methamphetamine users. Typically located somewhat in the middle of nowhere allowing multiple meth labs to operate.
I've heard about (pick a city or town slightly out of the way in the middle of nowhere) as being a total Tweakerville!
by tweaked_beauty August 03, 2009

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