If the number of people engaged in Twex is four or more, it is properly tagged #Tworgy. If the number of Tweeple is three and they are F/M/F, it is tagged #Tweesome. If the number of people engaged is just two, it is simply Twex.
Posted by User1:
OMG I had the best #twex last night. Me and @user2 with this chick, @user3.
Posted by User69:
@user1 Dude that wasn't #twex, you moron, that was a freaking #twangbang.