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Trucker's Knuckles refers to a severe case of multiple, external anal hemorrhoids that are raging and irritated and have a thrombosed clot under the skin causing a hard, painful lump appearing like the knuckles on a hand. Trucker's Knuckles often occur regularly to those individuals employed in long haul, over the road, driving professions.
Stan: Hey Frank. Are you heading on that haul from Chicago to L.A?
Frank: Yea and not looking forward to it.

Stan: Why?

Frank: I got the worst case of Trucker's Knuckles. Take a look. (Drops pants).
Stan: Holy Shit. Looks like a tiny fist down there. Better get some salve before you hit the road.
by Stan's Trucker's Knuckles April 15, 2014

Words related to Trucker's Knuckles

ass pain fist hemorrhoid knot knuckle prep h roid thrombosis