1. An amazing woman with many wonderful qualities, all of which are overshadowed by her breasts.

Guy: "Wow, did you see her tits?! Those are incredible"
Girl: "She just found a cure for AIDs and resolved the energy crisis, and all you can focus on are her boobs?"
Guy: "What can I say? She's a real Tits McGhee"
by Tiffany "Titz McGhee" June 20, 2008
A girl who has large boobs that are perfectly round.
Guy: Dude! Check out that tits McGhee over there, her boobs are SMOKIN!
by Kylie Hope May 23, 2006
A girl that has to plan her day around the twins.

Also, spoken of in Anchorman.
I'm Veronica Corningstone, Tits McGhee is on vacation.
by PTM & HFC August 14, 2006

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