look up any word, like dirty sanchez:
 
1.
v. to restrict blood flow in order to administer heroin intraveneously.
"i caught him with a belt ready to tie off."
by wayfarer April 27, 2005
 
2.
to hook a personal lanyard to a horizontal lifeline system or other safety device.
He will tie off to the safety rope.
by lizzyb June 02, 2007
 
3.
Office slang : masturbate furiously while at work. Usually in a conspicuous space and getting away with it.
Gareth said he was going to the photocopier to tie off.
by Mr John Gilbert esq. July 14, 2006
 
4.
To be patient, to hang on and wait
I don't care if you have been waiting all day. Just tie off, I will be there as soon as I can.
by Heather February 26, 2004