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1.
When someone acts in a way that is considered abnormally crazy, insane, or severly inbalanced. Also, used to describe someone who is oblivious to their surrounding causing them to be rude, obnoxious, or just annoiying to you.
"She must be three shades of crazy if she thinks she's gonna cut in front of me."

"You know he's three shades of crazy."

"Honey, I have bad news, I went to the Doctor today and they diagnosed me as three shades of crazy."
by VIZBR October 03, 2011