Top Definition
To travel a great distance round trip in one night just to possibly get turned down for some pussy by some hoe that don't even like you. Most thirst missions are usually accomplished by young men seeking the everlasting feeling of success of smashing on a young west coast damsel.
Ryan drove all the way to San Jose on his thirst mission. Bitch never gave up the pussy so he had to head back to Sac.

Andrew made us hella mad when he ditched us to go on his thirst mission.

thirsty
by sanchmas April 08, 2014
5 Words related to Thirst Mission

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