This is from the song cowboy casanova. "The snake with blue eyes" was used as a term for someone who was sneaky and always showed up at the last second before others left. I consider a snake with blue eyes to be a kind of sly person. They have quick wits and they always look at you and most of the time you don't see them. Also they have blue eyes. It can be used as a nickname for a guy and a girl.
"The snake with blue eyes" girl one said looking across the room to the new kid, the one with blue eyes.
by St0rmW0lf December 11, 2012