When you have the worst diarrhea runs. The shit sometimes just drips out of your ass crack, and on the floor causing an embarrasing moment for everybody. These runs usually happen every ten to fifteen minutes or so and maybe not coincidentally occur after dinner. They are especially bad when a sports movie is playing. The problem has not been diagnosed scientifically yet but it is clearly an issue in modern america society.
College Student 1: Man that kid must have the runs like no other
College student 2: Yea I heard he had the mudslide of st. edwards
College Student 1: Dude don't fuck around i hope u are kidding
College Student 2: Nah man I'm serious I wouldn't wish that upon anyone though.
by Grinnell March 31, 2008

5 Words Related to The Mudslide of St. Edwards

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