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2.
A once great and 'vibrant' (read 'ghetto') district of San Francisco now being taken over by an invasion of carpet-bagging, carpet-munching, cracker-ass hipsters.

SFC Native #1: It's cool how The Mission is coming up and crime is going down.

SFC Native #2: Nah fooh, the rents are rising and there's all these annoying young gringos stupidos around, not the older kind that were just annoying but not stupid.

SFC Native #1: Yeah, I guess you can't have everything.
by Mescalito April 16, 2008
35 3
 
1.
One of the central districts of San Francisco, CA. It is the city's Latino district. It is famous for its historic buildings, its Mission burritos (the best in Northern California), and its murals.

Rich people who tour San Francisco for a limited time think that the Mission is the ghetto. That's kind of true, but the disdain some of these people take with them is unfortunate. The Mission district is large and complex, with variying socioeconomic areas, clusters of mini-communities, and several specialty stores found nowhere else. Native San Franciscans know it as one of the "cool" districts.
SF Person 1: My cousins from San Mateo are going to visit the city this weekend; I'm gonna take them to The Mission!

SF Person 2: Ah, The Mission! I want to go to The Mission, too!

SF Person 1: Come with us!

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Cousins from San Mateo: Ooh... is that graffiti on that tree? Oh no, are we going to be mugged? Why is that corner store selling guavas?
by Gukumatz June 25, 2006
72 11