Top definition
When opposites such as black and white, or chocolate and vanilla, come together to form something amazing. This happens in the musical world all the time and can happen almost anywhere. i.e. Nelly and Tim Mcgraw joinging forces to form the song "Over and Over Again". Also, the frozen treats we all love would be a Hoodsie Effect
Timmy: "Have you heard that song by Tupac featuring Elton John?"

Bobby: "Ghetto Gospel? Ya, that's The Hoodsie Effect at its best."
by mindblaster April 27, 2010
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