Top Definition
Actually, the Grim Reaper loses a bet & must become the best friend of Billy, a boy whose stupidity is beyond description, & Mandy, a brilliant - but sadistic, evil, selfish, intimidating & wise far beyond her years or anyone else's - little girl.
One time in The Grim Adventures of Billy & Mandy, an evil meteorite from outer space tried to suck out Billy's brain but found that he had none.

Mandy can often make the most frightening of underworld creatures cower in fear by the sheer force of her will.
by Lanegan September 25, 2006

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