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4.
It means that you agree with something or it also means yes. It also means to ask for head.
Hey Samantha! That's Wassup
by Orlando Castillo January 07, 2004
 
1.
Can be used in the place of "fa sho," as in to agree with another, or to give props to somebody for some tight shit
You heard I got that job at Nike?
That's wassup
by Cheezie October 14, 2004
 
2.
An term of agreement.
Zan: Yo, I got a 95% in my Event Management Class!
Orande: Oh Word? I got a 95% too!
Both: THAT'S WASSUP!
by Zans May 11, 2006
 
3.
Among the same lines as saying, 'okay', 'for sure', 'yeah' or 'awready'. Mostly used down in Texas.

friend #1: "what's going down tonight?..."
friend #2: "we gonna party like rockstars!!"
friend #1: "yo, thats was sup!!"

Joe: "let's get blazed?!?"
Mike: "uhh, thats was up!!"
by eddy cee March 14, 2008