Refers to Call of Duty: Modern Warfare 2. In every game you build up a killstreak, that eventually gets shot down by some jackweed. This jackweed is known as "That Guy", or someone who spends the whole game shooting peoples hopes, dreams, and AC-130's down.
That Guy shot down my chopper gunner before it could even get in the map. Now I have to get 14 kills by myself to get the nuke.
by Camp of Duty July 08, 2010

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(n.) A male notorious for his artistry in seducing the fairer sex.
Katie, despite her adamant claims, was beguiled when she met that guy beneath heaven's starry canvas.
by theFlannelVillain June 17, 2010

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A mysterious figure, often someone with mad skills. Every sport has a That Guy as does every branch of the Military. That Guy is often the topic of conversation among aspirants in these fields. Such as High School football players referring to That Guy on an NFL team or Soldiers referring to That Guy on the Special Forces Detachment.
Soldier 1: That Urban training was rough, beat my old best time though.

Soldier 2: Yeah me too, but That Guy smoked us.

Soldier 1: Yeah, who was That Guy?

Are you That Guy?
by Corpy007 April 27, 2010

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the one guy at the party thats passed out or ridiculously drunk
Guy 1: o yea dude charlie is passed out in the room back there
Guy 2: o damn... hes THAT guy
by the one that is ononimous November 04, 2009

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(N.)(that-guy)The guy who drives at night with those blue lights on his car AND his high beams on, but ONLY uses them when it's a perfectly clear night, and he shines them right into your bedroom just to wake you up before work. He does this multiple times a night just to make sure you don't go back to sleep.
He also drives behind people to make sure they can't see SHIT.
Boss: "Johnson, why are you late?!"
Johnson: "Yeah, you see, it was That Guy again...."
Boss: "Oh, don't sweat it then. That Guy's an asshole."

or

Guy 1 "Oh my fucking God, it's that guy again!"
Guy 2 "The black one? With the funny moustache?"
Guy 1 "No....."
Guy 2 "You mean the one with........ OH MY GOD! WHAT THE HELL IS THAT LIGHT?!"
Guy 1 " DON'T LOOK INTO THE LIGHT!"
Guy 2 " OH MY GOD, I CAN'T SEE, HOLY SHIT, I THINK WE'RE GONNA CRASH"
by Hady October 28, 2008

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That one friend of yours who who is a time and energy vampire, always asks for favors, and creates drama. Meanwhile, all your other friends are chill af and cause no problems with you.
I need a new best friend, even though I've known him for 20 years, he is totally that guy..
by SoNotThatGuy June 18, 2016

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Someone who at that moment is being a dumbass/asshole
Jake Fejer "I gotta show you guys something, its super important"

Us " yea what is it?"

Jake " Nah nevermind"

Us" Jake is that guy"
by Swoop God December 04, 2014

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