1) To express disappointment
2) Slang expression for an unfair/unfortunate event
1) Jeremy took it in the ass on that.
2) Paul took it in the ass when he invested in Worldcom stock
by BIATCH551 March 15, 2005
To be on the receiving end of anal sex
Haha! You take it in the ass! Nya nya nya nya nya
by iopq November 11, 2003

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