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4.
Mostly known in the game "Call of Duty: Modern Warfare 2". This is acquired by getting a 25 Killstreak (25 kills without dieing) on the online multiplayer game modes. When you activate this, there will be a ten second countdown until the match ends and your team automatically wins. This killstreak is basically what made Modern Warfare 2 a camp-fest and surprisingly all shitty players have it on as a killstreak but never get it....
User 1: Omg I am so getting a Tactical Nuke this game!
User 2: Nah you will probably camp to get it you douche nozzle!
User: 1 Stuff you I am a legit noob asshole!
by THisguywhoaddsstuff August 04, 2010
 
1.
The oh so fabled "TACTICAL NUKE" from Call of Duty:Moderwarfare 2. Every single noob immediately unlocks it although they will never be able to get it in game. It requires a 25 kill streak on multiplayer and you must either be the most epic gamer ever or a no life to use it. Either way, you just bombed the crap out of everyone and ended the game.
25 Kill Streaker with "Tactical Nuke": OMFG TACTICAL NUKE!!!!! -launches tactical nuke-

Every other player: Dude what the f- BOOM

Game over.
by PTRS Noob November 18, 2009
 
2.
In Multiplayer when a played has a killstreak of 25 kills in a row without dieing they will gain the tactical nuke. The tactical nuke, blows up the entire map and kills all players on BOTH teams (chicken don't die though weird.) The player's team automatically wins regardless of the current score. When a tactical nuke has been activated the player usually spams in the mic bragging and spins around in circles shooting his gun around like an idiot.
Rangers: "Enemy Tactical Nuke incoming, it's over!"
Rangers Player: NUUUUUUUU!
by gangstahhh1232432423 April 27, 2010
 
3.
Although the Tactical nuke is know mostly from the game "Call of Duty: Modern Warefare 2" it is an actual weapon of mass destruction, or WMD. The tactical nuke, in lay men's terms, is a nuclear weapon able to be used in many different situations. The technically correct term for a tactical nuke is a Tactical Nuclear Weapon (TNW).

The brothers and sisters of the TN are the gravity bomb, short range missiles, artillery shells, land mines, depth charges, and torpedos. Also in this category are SAM's.
The bomb droped on Hiroshima at the end of World War II was equal in power to that of a tactical nuke.
by DaHunterPunter December 13, 2010
 
5.
A Tactical Nuke is the Superior of all ugly girls. This Tactical Nuke defeats grenades, mines, torpedos, and even the infamous A bomb. If you ever encounter a Tactical Nuke, it's all over.
Shivan: Dude I've been talking to this girl shelly she's so hot.

Bob: Bro she's friends with that girl Demi Brancal she's a Tactical Nuke, so you might as well quit, because its ALL OVER.
by Chase Freyman May 11, 2011
 
6.
if a player gets a tactical nuke in modern warfare 2, that player and or his/her team will win.
OMFG we got a tactical nuke.
look at those 2 noobs tactical nuke boosting in the corner of the bushes with there tactical insertions.
by noobtoob January 19, 2010
 
7.
It is a term used to define a really ugly girl that is either fat or a total mess. It holds stronger description than the famous grenade, landmine or zoo creature.

I can be used to go above and beyond when describing a woman or girl that has outdone herself as a grenade.

A girl who is the epitome of being fat, ugly, a mess or a combo of these.
Yo, did you see that girl? She's a total tactical nuke.
by The Almighty P.Gotti February 01, 2011