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1.
'TYSO' stands for Take Your Shirt Off
When white college girls get drunk, they take their shirts off.

Girl 1: Hey girl, I can't wait to get crazy tonight at the Frat Party.
Girl 2: I know, samesies! I hope you get TYSO all over that bitch!
Girl 1: YAY!! TEAM TYSO!!!
by TeamTyso January 25, 2012
 
2.
Derogatory term used for someone who thinks they are a know it all. Occasionally also taking their shirt off to impress the same or opposite gender despite the fact that they have nothing to show.
Grayson is such a TYSO when females come around.
by series1000 February 28, 2007
 
3.
City in Sommerlund, in the Lone Wolf world. Not very important. Nothing much happens there.
It gets attacked in Lone Wolf 1 I think.
by Andy May 01, 2004