Top Definition
Time to Fuck Shit Up. Can be used in any situation where you are about to began fucking shit up.
Football player before game: TTFSU BITCHES!
Bro about to party the night away: TTFSU!
Dude about to do fun shit: TTFSU!
by aHink June 25, 2010
1 more definition
guy 1: you guys ready for the game
guy 2: HELL YA! TTFSU!
by JPR12345 January 13, 2010

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