Top Definition
Also called 'Sy Syndrome' for short. This phrase means the horrible urge to hump/rape/fuck anything and everything that moves, breathes, or doesn't. This is usually caused when your girlfriend leaves you for some stupid reason and you are left without a source of woman in your life.
Guy 1: Hey man, whats up? You've done nothing but fap today, we were gonna go have game night.
Guy 2: Sorry, havin' some real bad Sy Syndrome.

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Guy 1: So now that she left me, its been really boring around the house, I need some action.
Guy 2: Calm down dude, I think your getting Syriel Syndrome.

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Guy 1: I NEED VAGINA!!
Girl 1: SOMEONE GET HIM AWAY FROM ME.
Guy 2: Nah its fine, he just has Sy Syndrome, shut up and take it.
by JapsyKinnz December 31, 2010

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