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1.
A show on The WB starring hotties Jensen Ackles and Jared Padalecki as Dean and Sam Winchester, respectively. The duo fights monsters, demons and reapers as they search for their father and the creature that killed their mother 22 years ago.
Supernatural is the best show.
by JensenandJared February 24, 2006
 
2.
a awsome show that rocks the world and makes ugly people look good when they watch it!!
me:oh man that was way too good of a show!

ugly person:damm that was soo supernatural that i now have a girlfriend!
by yonas January 05, 2008
 
3.
The best show to ever exist. Two brothers, Sam and Dean Winchester go around the country hunting the supernatural.

Reasons to watch Supernatural: It has a great story-line, the acting is great, it can be funny, scary, sad and more, all in one episode. Sam and Dean AKA Jared Padalecki and Jensen Ackles are just about the most gorgeous men to walk the Earth and there are a million more that would take me ages to list.

Currently in it's 6th season and it's better than ever. Shows on the CW every Friday at 9pm. WATCH IT.
Supernatural is the best show to ever exist.

Girl: Omg! Have you watched the latest episode of Supernatural?
Friend: Hell yeah. It was amazing and Sam and Dean were as awesome as ever.
by SPNRocksMyWorld October 28, 2010
 
4.
A show that will rip out your heart and stomp on it

Is also one of the main fandoms on Tumblr, and generally used to create the crossover Superwholock
'Are you okay?'
'No, I was watching Supernatural.'
'Oh, okay. I'm here for you bro.'
by I-know-I'm-Crazy June 17, 2013
 
5.
Relating to the realm of the unexplained.
Buddhist jerks believe that their dead cat still roams their house in the form of some supernatural entity.
by GuidoPosse69 February 22, 2005
 
6.
1) an organic action hero 2) a vegetarian action hero
In today's politically correct climate there would be a strong push to have Clark Kent drop the sexist name of Superman and change it to the more environmentally friendly and neutral "SUPERNATURAL" defender of all things pure and organic.
by JonnieS August 30, 2009
 
7.
n. or adj. Something which, by definition, does not exist.
See also woo-woo.
Describing something which is currently unknown as 'supernatural' is an easy way to avoid finding out real answers about the world.
by Zamzara October 10, 2007